Depression Evaluation Service (DES)

The DES offers free evaluation and medication treatment of depression through participation in treatment studies in midtown Manhattan and upper Manhattan locations. Our goal is to develop new scientific knowledge about the cause and treatment of clinical depressive disorders. All treatment is supervised by doctors on the faculty of the Columbia University Department of Psychiatry.

The DES has participated in several landmark multi-site clinical trials sponsored by the National Institutes of Mental Health (NIMH), including Sequenced Treatment Alternatives to Relieve Depression (STAR*D), Combining Medications to Enhance Depression Outcomes (COMED), and Combining Antidepressants to Hasten Remission from Depression (Dual Therapy).

New initiatives include the exploration of neurobiological mechanisms that may identify disease processes that affect treatment response. These initiatives utilize several sophisticated brain measurements, including Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), and Electroencephalographic (EEG) brain wave measurements.

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